Medical
Evidences

Medical Evidences

IS OPAT SAFE AND EFFECTIVE?

In an observational study involving older patients with a wide range of infectious diseases, self-outpatient parenteral antibiotic therapy (s-OPAT) by patients or their caregiver via a portable, disposable, continuous-infusion elastomeric pumps was safe and effective in the treatment of infections in older people.

Mujal, A., Sola, J., Hernandez., Villarino, MA., Baylina, M., Tajan, J., & Oristrell, J. (2015). Safety and effectiveness of outpatient parenteral antimicrobial therapy in older people. J Antimicrobial Chemotherapy 71(5):1402-7.

IS OPAT COST-EFFECTIVE?

In selected patients with infective endocarditis, treatment based on self-outpatient parenteral antibiotic therapy (s-OPAT) supported by a shortening hospital admission care program is a safe and efficient care model which entails a significant cost saving…application of the s-OPAT model based on hospitalization-at home unit meant a cost reduction of 32.72%.

Pajaron, M., Lisa, M., Fernandez-Miera, M.F., Duenas, J.C., Allende, I, Arnaiz, A, M., Sanroma-Mendizabal, P., de Berrazueta, J.R., & Farinas, M.C. (2017). Efficiency of a self-administered outpatient parenteral antimicrobial therapy (s-opat) for infective endocarditis within the context of a shortened hospital admission based on hospital at home program. Hospital Practice 45(5): 246-252.

Is the elastomeric pump a viable option to continuous infusion of IV antibiotics?

In this prospective observational study, patients in OPAT using elastomeric pumps for the continuous administration of the different kinds of antibiotics is efficacious and safe. Drug concentration measurements, considered a proxy for efficacy, confirm adequate circulating antibiotic exposures consistent with the observed high rate of therapeutic success.

Voumard, R., Gardiol, C., Andre, P., Arensdorff, L., Cochet, C., Boillat-Blanco, N., Decosterd, L., Buclin, T., & de Valliere, S. (2018). Efficacy and safety of continuous infusions with elastomeric pumps for outpatient parenteral antimicrobial therapy (OPAT): an observational study.J Antimicrobial Chemother 73(9): 2540-2545.

IS OPAT SAFE AND EFFECTIVE?

In an observational study involving older patients with a wide range of infectious diseases, self-outpatient parenteral antibiotic therapy (s-OPAT) by patients or their caregiver via a portable, disposable, continuous-infusion elastomeric pumps was safe and effective in the treatment of infections in older people.

Mujal, A., Sola, J., Hernandez., Villarino, MA., Baylina, M., Tajan, J., & Oristrell, J. (2015). Safety and effectiveness of outpatient parenteral antimicrobial therapy in older people. J Antimicrobial Chemotherapy 71(5):1402-7.

IS OPAT COST-EFFECTIVE?

In selected patients with infective endocarditis, treatment based on self-outpatient parenteral antibiotic therapy (s-OPAT) supported by a shortening hospital admission care program is a safe and efficient care model which entails a significant cost saving…application of the s-OPAT model based on hospitalization-at home unit meant a cost reduction of 32.72%.

Pajaron, M., Lisa, M., Fernandez-Miera, M.F., Duenas, J.C., Allende, I, Arnaiz, A, M., Sanroma-Mendizabal, P., de Berrazueta, J.R., & Farinas, M.C. (2017). Efficiency of a self-administered outpatient parenteral antimicrobial therapy (s-opat) for infective endocarditis within the context of a shortened hospital admission based on hospital at home program. Hospital Practice 45(5): 246-252.

Is the elastomeric pump a viable option to continuous infusion of IV antibiotics?

In this prospective observational study, patients in OPAT using elastomeric pumps for the continuous administration of the different kinds of antibiotics is efficacious and safe. Drug concentration measurements, considered a proxy for efficacy, confirm adequate circulating antibiotic exposures consistent with the observed high rate of therapeutic success.

Voumard, R., Gardiol, C., Andre, P., Arensdorff, L., Cochet, C., Boillat-Blanco, N., Decosterd, L., Buclin, T., & de Valliere, S. (2018). Efficacy and safety of continuous infusions with elastomeric pumps for outpatient parenteral antimicrobial therapy (OPAT): an observational study.J Antimicrobial Chemother 73(9): 2540-2545.

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